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Primary biliary cholangitis (PBC) - a disease with many faces
In PBC, the small bile ducts in the liver are damaged by autoimmune processes. If left untreated, this can lead to an inflammatory process that also affects the surrounding liver cells and can lead to scarring of the liver tissue (cirrhosis).
PBC is one of the rare diseases and has very different distributions around the world. In Germany, the number of PBC patients is estimated at around 35,000, of whom around 30,000 are in therapy. The majority of those affected are middle-aged women. The therapeutic options to prevent progression of PBC are good, but there is still a clear need for action in the area of symptom management.